Onyx Pharmaceuticals To Present At Cowen And Company Health Care Conference

EMERYVILLE, Calif. — Mar. 11, 2008

Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will present at the Cowen and Company 28th Annual Health Care Conference on Tuesday, March 18, at 8:00 a.m. Eastern Time. Interested parties may access a live webcast of the presentation at:

http://www.corporate-ir.net/ireye/conflobby.zhtml?ticker=ONXX&item_id=1779883

It is recommended that listeners log on 15 minutes early in order to register and download any necessary software. For those unable to participate during the live webcast, a recorded replay of the presentation will be available within 24 hours of the completion of the presentation through April 18, 2008.

Onyx Pharmaceuticals, Inc. is a biopharmaceutical company committed to improving the lives of people with cancer by changing the way cancer is treatedTM. The company, in collaboration with Bayer HealthCare Pharmaceuticals, Inc., is developing and marketing Nexavar®, a small molecule drug. Nexavar is currently approved for the treatment of advanced kidney cancer and liver cancer. Additionally, Nexavar is being investigated in several ongoing trials in non-small cell lung cancer, melanoma, breast cancer, and other cancers. For more information about Onyx, visit the company’s website at www.onyx-pharm.com.

Nexavar® (sorafenib) tablets is a registered trademark of Bayer Pharmaceuticals Corporation.

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