Onyx Pharmaceuticals to Present at JPMorgan Healthcare Conference

EMERYVILLE, Calif. — Jan. 05, 2006

Contact:
Julie Wood
510-597-6505

Onyx Pharmaceuticals, Inc. (Nasdaq:  ONXX) today announced that it will present at the JPMorgan Healthcare Conference on Thursday, January 12, at 12:00 p.m. Pacific Time. Interested parties may access a live webcast of the presentation at:

http://equityconferences.jpmorgan.com

It is recommended that listeners log on 15 minutes early in order to register and download any necessary software. For those unable to participate during the live webcast, a recorded replay of the presentation will be available within 24 hours of the completion of the presentation through February 12, 2006.

Onyx Pharmaceuticals is engaged in the development of novel cancer therapies that target the molecular basis of cancer. With its collaborators, the company is developing small molecule drugs, including Nexavar® (sorafenib) tablets with Bayer Pharmaceuticals Corporation. For more information about Onyx’s pipeline and activities, visit the company’s website at www.onyx-pharm.com.

Nexavar® (sorafenib) tablets is a registered trademark of Bayer Pharmaceuticals Corporation.

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