Onyx Pharmaceuticals to Present at Upcoming Healthcare Conferences

Richmond, California — Jun. 07, 2004

Contact:
Julie Wood
510-262-8757

Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will present at two investment conferences in June.

Goldman Sachs Twenty Fifth Annual Global Healthcare Conference
The first presentation will be at the Goldman Sachs Twenty Fifth Annual Global Healthcare Conference in Laguna Niguel, California, on Wednesday, June 9, at 4:00 p.m. Pacific Time. Interested parties may access a live webcast of the presentation by clicking on the link below:

http://customer.talkpoint.com/GOLD006/060704a_mk/default.asp?entity=onyx

Needham & Company Third Annual Biotechnology Conference
Subsequently, Onyx will present at the Needham & Company Third Annual Biotechnology Conference in New York City on Thursday, June 17, at 9:00 a.m. Eastern Time. Interested parties may access a live webcast of the presentation at:

http://www.wsw.com/webcast/needham8/onxx/

It is recommended that viewers log on 15 minutes early in order to register and download any necessary software. If you are unable to participate during either of the live webcasts, a recorded replay of the presentations will be available within 24 hours of the completion of the presentations. The replays will remain available for one month following the presentation dates.

Onyx Pharmaceuticals is engaged in the development of novel cancer therapies that target the molecular basis of cancer. With its collaborators, the company is developing small molecule drugs, including BAY 43 9006 with Bayer Pharmaceuticals Corporation. For more information about Onyx's pipeline and activities, visit the company's website at www.onyx pharm.com.

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