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ONYX PHARMACEUTICALS TO PRESENT AT TWO UPCOMING HEALTHCARE CONFERENCES
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Onyx Pharmaceuticals to Present at Two Upcoming Healthcare Conferences

Onyx Pharmaceuticals to Present at Two Upcoming Healthcare Conferences

Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will present at two healthcare conferences in January.

Emeryville, CA — Jan. 04, 2005

Contact:
Julie Wood
510-597-6505

JPMorgan Healthcare Conference
Onyx will present at The JPMorgan Healthcare Conference in San Francisco, California, on January 13, 2005 at 12:30 p.m. Pacific Time. Interested parties may access a live webcast of the presentation at:

http://equityconferences.jpmorgan.com

Piper Jaffray Healthcare Conference
Subsequently, Onyx will present at the Piper Jaffray Healthcare Conference in New York, New York, on January 25, 2005 at 9:30 a.m. Eastern Time. Interested parties may access a live webcast of the presentation at:

http://www.corporate-ir.net/ireye/confLobby.zhtml?ticker=ONXX&item_id=981161

It is recommended that listeners log on 15 minutes early in order to register and download any necessary software. If you are unable to participate during either of the live webcasts, a recorded replay of the presentations will be available within 24 hours of the completion of the presentations. The replays will generally be available for one month following the presentation dates.

Onyx Pharmaceuticals is engaged in the development of novel cancer therapies that target the molecular basis of cancer. With its collaborators, the company is developing small molecule drugs, including BAY 43-9006 with Bayer Pharmaceuticals Corporation. For more information about Onyx's pipeline and activities, visit the company's website at www.onyx pharm.com.

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