Onyx Pharmaceuticals to Present at Smith Barney Citigroup Small and Mid-Cap Conference

Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will present at the Smith Barney Citigroup Small and Mid-Cap conference on Wednesday, February 16, at 3:05 p.m. Pacific Time. Interested parties may access a live webcast of the presentation at:

http://www.veracast.com/webcasts/sbcitigroup/smc05/24110156.cfm

It is recommended that listeners log on 15 minutes early in order to register and download any necessary software. If you are unable to participate during the live webcast, a recorded replay of the presentation will be available within 24 hours of the completion of the presentation through March 16, 2005.

Onyx Pharmaceuticals is engaged in the development of novel cancer therapies that target the molecular basis of cancer. With its collaborators, the company is developing small molecule drugs, including BAY 43-9006 with Bayer Pharmaceuticals Corporation. For more information about Onyx’s pipeline and activities, visit the company’s website at www.onyx pharm.com.

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